视神经炎临床分型与水通道蛋白4抗体被引量：3

下载PDF

导出

摘要视神经炎(optic neuritis,ON)临床分型较为复杂。其中特发性脱髓鞘性ON与经典多发性硬化关系密切,而其他免疫介导性ON的发病机制和临床转归尚不明确。水通道蛋白4抗体作为对视神经脊髓炎(NMO)诊断敏感度和特异度较高的自身免疫抗体,在复发性ON和视功能恢复较差的ON患者中阳性率高,而且抗体阳性的ON更易发生脊髓损害或进展成为NMO。

作者颜榕张晓君

机构地区首都医科大学附属北京同仁医院神经内科

出处《中国神经免疫学和神经病学杂志》 CAS 2011年第4期293-295,共3页 Chinese Journal of Neuroimmunology and Neurology

关键词视神经炎多发性硬化视神经脊髓炎水通道蛋白4抗体

分类号 R774.61 [医药卫生—眼科]

引文网络
相关文献

参考文献17

1Lennon VA, Wingerchuk DM, Kryzer TJ,et at. A serum au- toantibody marker of neuromyelitis optica: distinction from multiple sclerosis[J]. Lancet, 2004,364 : 2106-2112.
2Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of op- tic-spinal multiple sclerosis binds to the aquaporin-4 water channel[J]. J Exp Med, 2005,202 : 473-477.
3Smith CH. Walsh and Hoyt's Clinical Neuroophthalmololy [M]. In.. Optic neuritis[M]. 6th ed. Baltimore Maryland USA : Lippincott Williams & Wilkins, 2005. 293-326.
4Optic Neuritis Study Group. High and low-risk profiles for the development of multiple sclerosis within 10 year after optic neuritis[J]. Arch Ophthalmol, 2003,121 : 944-949.
5张晓君,彭静婷,贾楠.特发性脱髓鞘性视神经炎的临床转归[J].中华神经科杂志,2009,42(1):20-24. 被引量：7
6Petzold A, Pittock S, Lennon V,et al. Neuromyelitis optica- IgG (aquaporin-4) autoantibodies in immune mediated optic neuritis[J].J Neurol Neurosurg Psychiatry, 2010, 81:109- 111.
7Wingerchuk DM, Lennon VA, Lucchinetti CF, et al. The spectrum of neuromyelitis optica[J].Lancet Neurol, 2007,6 :805-815.
8张晓君,彭静婷,贾楠,王越,王光璐.自身免疫性视神经病临床研究[J].中华眼底病杂志,2009,25(6):447-450. 被引量：10
9Wang JC, Tow S, Aung T, et al. The presentation, etiology, management and outcome oF optic neuritis in an Asian popula- tion[J]. Clin Experiment Opthalmol,2001,29:312-315.
10Zhang X, Wang W, Wei W, et al. Etiological profile of pre- sumptive optic neuritis in China[J].J Clin Neurosei,2008, 15 (12) : 1346-1349.

二级参考文献12

1张晓君,王薇,王虔,魏文斌,魏永祥.视神经炎病因学临床分析[J].中华眼底病杂志,2006,22(6):367-369. 被引量：58
2Smith CH. Optic neuritis//Miller NR, Newman NJ, Biousse V, et al. Walsh and hoyt clinical neuro ophthalmology. 6th ed. Baltimore: Lippincott Williams & Wilkins, 2005:293-326.
3Goodwin J. Autoimmune optic neuropathy. Curr Neurol Neurosci Rep, 2006,6:296-402.
4Zhang X, Wang W, Wang Q, et al. Clinical features of optic neuritis in China. Neuro Ophthalmol, 2007, 31:133-136.
5Optic Neuritis Study Group. The 5-year risk of MS after optic neuritis: experience of the optic neuritis treatment trial. Neurology,1997, 49: 1404-1413.
6Kupersmith MJ, Burde R, Warren F, et al. Autoimmune optic neuropathy: evaluation and treatment. J Neurosurg Psyehia, 1988,51:1381-1386.
7Kurokawa MS, Suzuki N. Behcet's disease. Clin Exp Med, 2004,3:10-20.
8Cree BA, Goodin DS, Hauser SL. Neuromyelitis optica. Semin Neurol,2002,22: 105-122.
9Hummers LK, Krishnan C, Casciola-Rosen L, et al. Recurrent transverse myelitis associates with anti-Ro ( SSA ) autoantibodies. Neurology,2004, 62: 147-149.
10彭静婷,张晓君,崔世磊,张风,周海英.儿童视神经炎病因分析[J].中华眼底病杂志,2008,24(2):95-98. 被引量：8