大黄治疗脑出血急性期的临床观察

Clinical Efficacy of Rhubarb in Treating Acute cerebral hemorrhage

目的:观察大黄治疗脑出血急性期的临床疗效。方法:将符合条件的64例患者随机分为治疗组(大黄+常规治疗)33例和对照组(常规治疗)31例。采用NIHSS评分、mRankin残障评级和Barthel指数(BI)评价疗效,并比较治疗前后出血量。结果:以90d为试验终点,NIHSS评分对照组为5.86±4.91,治疗组为4.67±3.39;治疗后出血量对照组为(12.23±6.50)mL,治疗组为(8.85±5.71)mL。上述指标2组比较差异均有统计学意义(P<0.05)。mRankin残障评级及BI评分,2组比较差异无统计学意义。结论:大黄治疗脑出血急性期患者安全、有效、简单易行。

Objective：To observe the curative effect of Rhubarb on acute cerebral hemorrhage（ACH）.Methods：A total of 64 ACH patients were randomly assigned to two groups.The control group（31 cases） was treated with medicine and the treated group（33 cases）was given Rhubarb on the basis of medicine.The end point was set at the 90th day of the administration.The curative effect was assessed by National Institutes of Health Stroke Scale（NIHSS） score,mRankin scale and Barthel index（BI）.Results：At the end point of the trial,NIHSS score in control group was 5.68±4.91 and treatment group was 4.67±3.39;After treatment,amount of bleeding in control group was（12.23 ± 6.50）mL and treatment group was（8.85 ± 5.71）mL.Comparison between them showed significant differences（P0.05）.There was no significant differences between the control group and the treatment group in the mRankin scale and Barthel index.Conclusions：Rhubarb combined with Western medicine shows better safety and curative efficacy on ACH.