中国三地区女性性工作者对杀微生物剂的可接受性及其影响因素研究

Vaginal microbicides acceptability and its influencing factors among female sex workers in three areas of China

目的探索女性性工作者(female sex workers,FSWs)对阴道外用杀微生物剂的可接受性及其影响因素。方法采用横断面调查的方法,于2008年9月至2009年1月在云南德宏、四川乐山和辽宁沈阳3现场共抽取968名FSWs作为研究对象,以面对面访谈方式进行问卷调查。主要评价指标包括杀微生物剂可接受性得分、危险性行为、安全套使用率、性病史、艾滋病/性病感知风险等。结果被调查的FSWs对杀微生物剂的可接受性平均得分为(2.88±0.58)分。可接受性受FSWs的所在地区、性服务场所的档次与性质、年龄、文化程度、是否主动要求使用和被拒绝使用安全套、是否检测过HIV抗体、是否担心感染艾滋病/性病、妊娠史和阴道外用药史等因素影响。结论接受调查的FSWs对使用杀微生物剂的态度普遍较积极,提示杀微生物剂有可能作为安全套的补充措施,满足女性在艾滋病/性病预防中的特殊需要。

Objective To explore attitudes and willingness towards vaginal microbicides use among female sex workers （FSWs） for HIV/AIDS and sexually transmitted infection （STI） prevention, as well as its related factors. Meth- ods A cross-sectional study was conducted in Dehong, Yunnan Province, Leshan, Sichuan Province and Shenyang, Liaoning Province from September 2008 to January 2009. A total of 968 FSWs were sampled to participate in face to face interviews. Main outcome variables were measured by microbicide acceptability score with questionnaire, including high- risk sexual behaviors, self-reported condom use, self-reported HIV/STI history and perception of HIV/STI risk, etc. Re- suits Mean score of microbicide acceptability in FSWs was 2.88 _＋ 0.58. Acceptability score varied by study sites, tier and function of sex establishments, age, educational level, if have asked for and been refused for condom use, experience of HIV testing, concerns about contracting HIV/STI, history of pregnancy and vaginal product experience. Conclusions FSWs might have a positive response to vaginal microbicides use across all hypothetical characteristics in general, indi- cating microbicides may act as supplements to condom and further, satisfy women＇ s special needs in HIV/STI prevention.