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经皮穴位电刺激对全麻行控制性降压期间胃粘膜PHi、PgCO_2的影响 被引量:5

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摘要 目的:观察经皮穴位电刺激(TAES)对控制性降压麻醉中胃粘膜PHi、二氧化碳分压(Pg-CO2)等的影响,探讨TAES对胃粘膜的保护作用。方法:选择脑膜瘤病人42例,年龄20-65岁,美国麻醉师协会(ASA)分级Ⅰ-Ⅱ级。随机分为单纯全麻组(S组)和TAES复合药物全麻组(C组)各21例。S组在脑膜打开后输注硝酸甘油复合艾司洛尔行控制性降压,使平均动脉压(MAP)平稳降至目标MAP水平(55-65mmHg)。C组麻醉前30min行TAES,并于术中间断行TAES至手术结束。分别监测降压开始前(TO)、降压至目标MAP后30rain(T1)、60min(T2)、停止降压后30rain(T3)、60rain(T4)各个时间点血压和心率的变化情况以及测定各个时间点动脉过程危险分析(PHa)、PgC02等,同时通过输入动脉血压、PgC02等数值,利用Tonocap胃粘膜二氧化碳张力测定仪测定胃粘膜PHi、PgCO。等。结果:S纽:与TO比较,T1胃粘膜PHi值降低,有显著性差异(P〈O.05),PgC02值无显著性改变(P〉0.05);C组:T1、T2、T3、T4胃粘膜PHi值和PgC02值与TO比较无显著性差异(P〉0.05)。组间比较,在T1时间点,C组和S组比较,胃粘膜PHi值显著性升高(P〈0.05),PgCO。值无显著性改变(P〉0.05)。结论:全麻控制性降压期间可出现胃粘膜灌注一过性降低,而经皮穴位电刺激通过维持胃粘膜PHi的稳定,达到保护胃粘膜作用。
出处 《浙江中医杂志》 2011年第7期472-475,共4页 Zhejiang Journal of Traditional Chinese Medicine
基金 国家科技部973计划课题针药复合麻醉中镇痛与血压调控的相关性机制及对脏器保护效应的研究 编号:2007CB512506
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参考文献18

  • 1Calvet X,Baigorri F,Duarte M,et al. Effect of sucralfate on gastric intramucosal pH in critically ill patients[J]. Intensive Care Med,1997,23(7) :738-742.
  • 2Taylor DE, Gutierrez G, Tonometry. A review of clinical studies[J]. Crit Care Clin,1996,12(4) :1007-1018.
  • 3Oud L, Kruse JA. Progressive gastric intramucosal acidosis follows resuscitation from hemorrhagic shock[J]. Shock, 1996,6 (1):61-65.
  • 4Santoso JT,Wisner DH, Battistella FD, et al. Comparison of gastric mucosal pH and clinical judgement in critically ill patients [J]. Eur J Surg,1998,164(7) :521-526.
  • 5章彦,许幸,苑贵敏,陈晓菲,孙晓雄.髋部手术全麻患者硝普钠或尼卡地平控制性降压的安全性[J].中华麻醉学杂志,2006,26(3):199-203. 被引量:5
  • 6Yosry M, Othman IS. Controlled hypotension in adults un dergoing choroidal melanoma resection:comparison between the efficacy of nitroprusside and magnesium sulphate[J]. Eur J An aesthesiol, 2008,25 (11) : 891-896.
  • 7Takala J. Determinants of splanchnic blood flow[J]. Br J An aesth, 1996,77(1) :50-58.
  • 8Knichwitz G, Rotker J, Mollhoff T, et al. Continuous in tramucosal PgCO2 measurement allows the early detection of in testinal malperfusion[J]. Crit Care Med, 1998,26(9) : 1550-1557.
  • 9Tang W, Weil M H, Sun S, et al. Gastric intramural PgCO2 as monitor of perfusion failure during hemorrhagic and anaphylactic shock[J]. J Appl Physiol, 1994,76(2): 572-577.
  • 10Guzman JA,Lacoma FJ ,Kruse JA. Relationship between systemic oxygen supply dependency and gastric intramucosal PgCO2 during progressive hemorrhage[J]. J Trauma, 1998,44 (4) : 696-700.

二级参考文献45

  • 1黄忠,李铁,于吉人,马大龙.白介素-1β对大鼠应激性胃粘膜损伤的保护作用[J].生理学报,1995,47(4):313-319. 被引量:15
  • 2孙绍金,黄裕新,许才绂.内皮素对胃肠损伤作用机制的研究进展[J].新消化病学杂志,1996,4(4):224-225. 被引量:8
  • 3王吉村,孙长凯,李霓,李伟.一氧化氮在消化系统及其疾病中的作用[J].国外医学(消化系疾病分册),1996,16(1):35-39. 被引量:35
  • 4许冠荪,王振玖,朱舜丽,陈全珠,焦洁,张道芹.一氧化氮参与针刺对大鼠胃粘膜损伤的保护作用[J].安徽中医学院学报,1996,15(3):36-38. 被引量:14
  • 5赵平,凌亦凌.胃肠激素与危重症胃肠功能障碍的研究进展[J].中国危重病急救医学,2006,18(10):634-636. 被引量:36
  • 6汪建英 李振甲.6-keto-PGF1α和TXB2在胃粘膜适应性细胞保护中的作用[J].生理学报,1986,38(5):451-458.
  • 7Alebouyeh N, Toefigh M, Ghasemzadeh N, Mirheydari S, Azargashb E. Predictors of gastrointestinal perforation in patients undergoing coronary artery bypass graft (CABG) surgery in Tehran, Iran. Ann Thorac Cardiovasc Surg 2007; 13: 251-253
  • 8Geissler HJ, Fischer UM, Grunert S, Kuhn-Regnier F, Hoelscher A, Schwinger RH, Mehlhorn U, Hekmat K. Incidence and outcome of gastrointestinal complications after cardiopulmonary bypass. Interact Cardiovasc Thorac Surg 2006; 5:239-242
  • 9Yamaura K, Okamoto H, Akiyoshi K, Irita K, Taniyama T, Takahashi S. Effect of lowdose milrinone on gastric intramucosal pH and systemic inflammation after hypothermic cardiopulmonary bypass. J Cardiothorac Vasc Anesth 2001; 15:197-203
  • 10McSweeney ME, Garwood S, Levin J, Marino MR, Wang SX, Kardatzke D, Mangano DT, Wolman RL. Adverse gastrointestinal complications after cardiopulmonary bypass: can outcome be predicted from preoperative risk factors? Anesth Analg 2004; 98: 1610-1617, table of contents

共引文献95

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  • 1黄仕荣.针刺促微循环镇痛机制研究与思考[J].中国中医药信息杂志,2006,13(2):97-99. 被引量:24
  • 2黄艾,阳仁达,严洁,黎喜平,常小荣,易受乡,林亚平.电针对应激性胃黏膜损伤大鼠UI、GMBF及胃黏膜形态学的影响[J].中国中医基础医学杂志,2006,12(8):637-639. 被引量:9
  • 3陈兰,刘诗.高频电针刺激足三里促进大鼠结肠推进运动[J].世界华人消化杂志,2006,14(30):2962-2964. 被引量:9
  • 4Chernyak G V,Sessler D I.Perioperative acupunctureand related techniques[J].Anesthesiology,2005,102(5):1031-1049,1077-1078.
  • 5Gioia L,Cabrini L,Gemma M,et al.Sedative effectof acupuncture during cataract surgery:prospectiverandomized double-blind study[J].J Cataract RefractSurg,2006,32(11):1951-1954.
  • 6Sun Y,Gan T J,Dubose J W,et al.Acupuncture andrelated techniques for postoperative pain:a systematicreview of randomized controlled trials[J].Br J An-aesth,2008,101(2):151-160.
  • 7Alimi D,Rubino C,Pichard-Leandri E,et al.Analge-sic effect of auricular acupuncture for cancer pain:arandomized,blinded,controlled trial[J].J Clin On-col,2003,21(22):4120-4126.
  • 8Paley C A,Johnson M I,Bennett M I.Should phys-iotherapists use acupuncture for treating patients withcancer-induced bone pain?A discussion paper[J].Physiotherapy,2011,97(3):256-263.
  • 9Ezzo J,Streitberger K,Schneider A.Cochrane sys-tematic reviews examine P6acupuncture-point stimu-lation for nausea and vomiting[J].J Altern Comple-ment Med,2006,12(S):489-495.
  • 10Liodden I,Howley M,Grimsgaard A S,et al.Perio-perative acupuncture and postoperative acupressurecan prevent postoperative vomiting following paedia-tric tonsillectomy or adenoidectomy:apragmatic ran-domised controlled trial[J].Acupunct Med,2011,29(1):9-15.

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