摘要
脑损伤是先天性心脏病婴幼儿围术期的常见并发症之一,病因较成人心脏病复杂,存在于整个围术期过程中,并有其独特的临床特点。其发病机制至今尚未完全明了,有学者认为进行心脏纠正手术体外循环时的再氧合损伤起重要作用。现将近年来关于先天性心脏病婴幼儿体外循环时动脉血氧分压与脑损伤的关系进行综述。
Brain injury is one of the common perioperative complications in infants with congenital heart disease,but its causative factors are more complicated than those in adult heart disease.The brain injury possesses its unique clinical characteristics and its pathogenesis remains to be well clarified.Reoxygenation injury during cardiopulmonary bypass is thought to be a key mechanism of neurological complications.Here discussed is the relationship of arterial oxygen partial pressure with brain injury during cardiopulmonary bypass in infants with congenital heart disease.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2011年第13期1039-1041,共3页
Journal of Applied Clinical Pediatrics
基金
国家科技支撑计划课题(2006BAI01A08)
广东省重点科技项目(2005B33801008)
广东省重点科技项目(2007B031507009)
关键词
心脏病
先天性
体外循环
动脉血氧分压
脑损伤
婴幼儿
congenital heart disease
cardiopulmonary bypass
arterial oxygen partial pressure
brain injury
infant
