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氯吡格雷抵抗的发生率和危险因素分析 被引量:12

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摘要 目的探讨氯吡格雷抵抗(CR)的发生率及其与心血管疾病危险因素的相关性。方法采用回顾性病例对照研究,根据血小板聚集抑制率(DPAI)及CR将患者分为正常组、半抵抗组和抵抗组,分析年龄、性别、吸烟、饮酒、肥胖、血压、血脂、血糖、尿酸和高敏C反应蛋白等与其的相关性。结果共调查107例心内科住院患者,平均血小板聚集抑制率(DPAI)(24.4±23.3)%(0~85%),CR的发生率为33.6%。并未发现以上冠心病危险因素与CR存在相关性。结论本研究中CR发生率较高,常见的危险因素与CR可能无关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第13期2434-2436,共3页 Chinese Journal of Gerontology
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