针刺与西药治疗肠易激综合征疗效对照观察

Comparative study on irritable bowel syndrome treated with acupuncture and western medicine

目的:比较针刺天枢、大肠俞为主与口服西药马来酸曲美布汀治疗肠易激综合征的疗效差异。方法:将40例患者随机分针刺组和西药组,每组20例。针刺组针刺天枢、大肠俞为主,采用子午捣臼法,每天1次;西药组口服马来酸曲美布汀胶囊,每次2粒,每日3次,两组均治疗4周后评定疗效。结果:两组患者治疗后腹痛时间、腹痛频率、排便形状异常比率、排便通过异常比率、黏液便比率、排便时腹胀或腹痛积分均较治疗前降低(均P<0.01),且针刺组较西药组降低更显著(总积分:16.70±2.40 vs 15.70±3.01,P<0.01)。针刺组总有效率为95.0%(19/20),优于西药组的70.0%(14/20)(P<0.05)。结论:针刺天枢、大肠俞为主可明显改善肠易激综合征患者的临床症状,其疗效优于口服西药马来酸曲美布汀。

Objective To compare the differences in the therapeutic effect on irritable bowel syndrome （IBS） between acupuncture at Tianshu （ST 25） and Dachangshu （BL 25） and western medication with Trimebutine Maleate. Methods Forty cases were divided randomly into an acupuncture group and a western medication group, 20 cases in each one. In acupuncture group, acupuncture was applied to Tianshu （ST 25） and Dachangshu （BL 25）. Ziwu Daojiu needling technique was adopted, once daily. In western medication group, Trimebutine Maleate capsule was administered, 2 capsules in each time, 3 times per day. The assessment on the therapeutic effect was performed in 4 weeks of treatment in two groups. Results As compared with those before treatment, the time of abdominal pain, the frequency of abdominal pain, the morbidity of abnormal stool appearance, the morbidity of defecation abnormality, the morbidity of mucus stool and the score of bloating or abdominal pain on bowel movement were all reduced after treatment in two groups （all P〈0.01）. The results in acupuncture group were much more significant than those in western medication group （the total score： 16.70 ± 2.40 vs 15.70 ± 3.01, P〈0.01）. The total effective rate in acupuncture group was 95.0% （19/20） , which was superior to that of 70.0% （14/20） in western medication group （P〈0.05）. Conclusion Acupuncture at Tianshu （ST 25） and Dachangshu （BL 25） may remarkably relieve the clinical symptoms of IBS and its efficacy is superior to that of oral medication with Trimebutine Maleate.