三种关于建立家兔人工气道方法的评价

Comparison of Three Methods for Setting up Artificial Airway of Rabbit

目的比较关于家兔三种人工气道(artificial airway,AA)建立方法,为实验中快速建立家兔人工气道选择较好的方法提供参考。方法选用新西兰大耳白兔共30只,随机均分为3组。分别采用气管切开法、经口明视气管插管法、经口盲探气管插管法建立人工气道,比较各组建立人工气道的时间,首次成功率及并发症发生情况。结果经口盲探气管插管法建立人工气道的时间明显短于经口明视气管插管法和气管切开法,首次成功率由高到低依次是气管切开法、经口盲探气管插管法、经口明视气管插管法。经口盲探气管插管组并发症发生率最低,为(10±5)%,气管切开组和经口明视气管插管组并发症发生率分别为(20±10)%,(30±10)%。结论经口盲探气管插管是现阶段建立家兔人工气道时值得优先考虑的方法,简便易行、可操作性强,成功率高。

Objective To compare three methods for setting up artificial airway（AA） of rabbit.Methods 30 New Zeland White rabbits were chosen and randomly divided into three groups： Group BOI（group blind orotracheal intubation）;Group COI（group classic orotracheal intubation）;Group TO（group tracheotomy）.The time for setting up artificial airway,the achievement ratio for the first time and the incidence of complication were observed.Results The shortest time for setting up artificial airway is Group BOI,showing a significant difference compared with other two groups（P 〈0.05）.The highest achievement ratio is Group TO,then Group BOI,and the lowest Group COI（P 〈0.05）.The highest incidence ratio of complication is Group TO,then Group COI,the lowest is Group BOI.Conclusions Blind intubation can be the first choice for setting up artificial airway for rabbit compared with classic oratracheal intubation and tracheotomy.