聚乙烯醇与真丝线段栓塞子宫动脉治疗子宫肌瘤的临床研究

Comparison of different embolism agents in uterine arterial embolizatlon therapy for leiomyoma of uterus

目的探讨不同栓塞剂行子宫动脉栓塞术治疗子宫肌瘤后的疗效、不良反应及并发症。方法 62例子宫肌瘤行选择性双侧子宫动脉插管造影栓塞治疗,其中32例用真丝线段栓塞(SS组),30例用聚乙烯醇栓塞(PVA组)。术后随访6个月,观察临床症状改变、肌瘤大小变化、术后不良反应及并发症。结果丝线组和PVA组贫血、月经量多、压迫症状均有不同程度不同改善。虽然UAE后6个月PVA组肌瘤缩小较多,但差异无统计学意义(P>0.05)。PVA组的UAE后发热率较丝线组增高(P=0.043 2),而其他不良反应及并发症两组间差异无统计学意义(P>0 05)。结论真丝线段和PVA行子宫动脉栓塞治疗子宫肌瘤均有明显疗效且不良反应发生率差别较小,是良好的UAE栓塞材料。

Objective To investigate the effectiveness,side effects and complications of uterine artery embolization（UAE） for uterine leiomyoma with different embolism agents.Methods A total of 62 patients underwent UAE by using either natural silk segment（Group SS,32patients） or polyvinyl alcohol（Group PVA,30 patients） after 6 months of follow up,clinical symptoms,tumor volumes,postoperative side effects and complications were observed respectively.Results There were no significant difference between the two group for volume of uterine leiomyoma,amelioration rate of anemia,menstrual cycle and oppression symptoms.The fever rates after UAE in patients using PVA were higher than those using silk segment;but other side effect and complication were no significant variation in the two groups either（P0 05）.Conclusions No substantive difference is detected between outcomes of embolization with silk segment and PVA.