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蛋白质组学技术在儿童疾病研究中的应用

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摘要 蛋白质组是指在细胞、器官或组织中表达的全部蛋白,包括所有的亚型及翻译后的变异体。蛋白质组学是研究蛋白质组的动态过程,具有时间和部位双重特性。差异显示性蛋白质组学或比较蛋白质组学是目前临床相关研究最有效的手段之一,即比较两种状态下(如正常人群和患病人群、年轻人和老年人、治疗前和治疗后等)蛋白表达及丰度上的不同。
出处 《中华儿科杂志》 CAS CSCD 北大核心 2011年第7期526-530,共5页 Chinese Journal of Pediatrics
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