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HAb18G/CD147在食管鳞状细胞癌中的表达及其临床意义 被引量:2

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摘要 目的:探讨HAb18G基因产物表达与食管鳞状细胞癌(ESCC)临床病理特征及预后的关系。方法:应用免疫组化SP染色法分析了108例食管鳞状细胞癌标本中HAb18G基因产物表达情况和定位,并对其进行了术后3年随访。结果:HAb18G基因产物在有淋巴结癌转移和预后差的食管鳞状细胞癌病例中高表达;HAb18G的高表达与食管鳞状细胞癌的浸润转移、分化程度均相关(P<0.05);淋巴结转移和HAb18G表达可作为食管鳞状细胞癌患者预后独立指标。结论:HAb18G在食管鳞状细胞癌中的表达与食管癌的发生发展、浸润转移和预后密切相关,可作为临床预测浸润转移和估计预后的一个重要参考指标。
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2011年第7期784-786,共3页 Chinese Journal of Cellular and Molecular Immunology
基金 国家高新技术研究发展计划(973)重点项目(2009CB521704) 国家自然科学基金资助项目(81001088 30672013 30800417)
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