黛力新治疗2型糖尿病患者合并抑郁症的疗效观察

Effect of Deanxit on type2 diabetes mellitus patients and depressive symptoms

目的探讨黛力新治疗2型糖尿病合并抑郁症的疗效。方法将60例合并抑郁症的2型糖尿病患者,随机分为治疗组(服用黛力新,30例)和对照组(未服用黛力新组,30例),治疗8周。以汉密尔顿抑郁量表(HAMD)评定疗效,用糖化血红蛋白(HbA1c)水平监测血糖控制情况。结果治疗8周后,治疗组抑郁症状的改善明显优于对照组(P<0.01),痊愈率(43.3%)和有效率(66.7%)均明显高于对照组(分别为16.7%和36.7%)(P<0.01);治疗组HbA1c水平较治疗前显著下降,且明显低于对照组(P<0.01)。结论黛力新能明显改善糖尿病患者的抑郁症状,更有利于患者血糖的控制。

Objective To explore the efficacy of Deanxit for treating type 2 diabetes mellitus（DM）patients and depressive symptorns.Methods A total of 60 type 2 DM patients with depression were divided into control group and treatment group.Control group was given conventional drugs,and treatment group was given both conventional drug and Deanxit for the treatment of 8 weeks.HAMD was used to assess efficacy.The control condition of blood glucose was detected go through.Results The healing rates and the response rates in treatment group and control group were 43.3% and 66.7%,16.7% and 36.7% respectiely,there had significant differences between two groups（P〈0.01）.Level of HbA1c in treatment group significantly decreased after 8-week treatment compared to control group（P〈0.01）.Conclusion Deanxit is effective not only for controlling depressive symptoms,but also for improving the controlling of blood glucose in pa-tients with type 2 diabetes mellitus.