儿童肥胖与性早熟关系的研究

Study on Realationship of Child Obesity and Precocious Puberty

目的了解儿童肥胖与性早熟发生之间的关系。方法以郑州地区3～12岁儿童为对象,采用分层随机整群抽样方法,共获取研究对象8750名,全部进行体格检查,进行描述性统计分析、卡方检验、趋势检验,检验水准α=0.05。结果超重和肥胖儿童中性早熟的检出率(1.4%)高于正常体重儿童(0.6%),差异有统计学意义(P=0.002);其中超重和肥胖女童性早熟的检出率(3.1%)高于正常体重女童(1.1%),差异有统计学意义(P=0.001);男童差异无统计学意义,随着肥胖度的增加女童性早熟的检出率呈上升趋势。结论郑州地区儿童肥胖与性早熟的发生密切相关,超重和肥胖儿童中性早熟的检出率高于正常体重儿童,且女童性早熟的发生与BM I的关系较男童更为密切,随着肥胖度的增加女童性早熟的检出率呈上升趋势。

Objective To explore the relationship between obesity and precocious puberty.Methods Totally 8750 children from 3 to 12 years old were selected from Zhengzhou by stratified and cluster sampling.All the individuals selected were medical examined,and the data was analyzed by descriptive statistics,Chi-square tests,tendency tests.Results The detection rates of precocious puberty in overweight and obesity children（1.4 %） was higher than that of the normal children（0.6%）,and the detection rates of precocious puberty in overweight and obesity girls（3.1%） was much higher than that of the normal girls（1.1%）,while there were no significance in boys.With the increase of the degree of obesity,the detection rates of precocious puberty also increased（t=10.629,P=0.001）.Conclusions There was close relationship between obesity and precocious puberty,and the detection rate of precocious puberty among the overweight and obese children was higher than normal weight children.The girls’ incidence of precocious puberty was colser with BMI than boys’,and with the increasing of the degree of obesity,the detection rates of precocious puberty also increased among girls