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干细胞治疗缺血性心脏病的临床价值 被引量：2

A clinical value of treating ischemic heart disease in stem cells
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摘要 最近研究发现人类心脏含有干细胞,这些干细胞具有产生心肌细胞和其他细胞的功能,这为心肌的完全修复提供了可能性。本文对干细胞治疗缺血性心脏病的临床价值方面的研究进展作一综述。 Recent studies have found that human heart contains stem cells, these stem cells have functions that generate cardiomyocytes and other cell, which provide the possibility of myocardial complete restoration. This paper overviewed the clinical value of treating ischemic heart disease in stem cells.
作者 周瑶 褚海涛 史记
机构地区 中国医科大学
出处 《中医临床研究》 2011年第13期115-116,共2页 Clinical Journal Of Chinese Medicine
关键词 干细胞 缺血性心脏病 急性心肌梗死 Stem cells Ischemic heart disease Acute myocardial infarction
分类号 R541.5 [医药卫生—心血管疾病]
  • 相关文献

参考文献8

  • 1WOOCHUL CHANG, et al.Mesenchymal Stem Cells Pretreated with Delive-red Hph-l-Hsp70Protein Are Protected from Hypoxia-Mediated Cell Death andRescueHeart Functions from Myocardial Injury[J].STEM CELLS,2009;27:2283-2292.
  • 2Schinger V, et al.Intracoronary bone mar-row-derived progenitor cells in acu-te myocardial infarction [J].NEngl J Med,2006,355:1210-1221.
  • 3Assmus B,et al.Transcoronary trans-plantation of progenitor cells after myoc-ardial Infarction[J].N Engl J Med,2006,355:1222-1232.
  • 4李延林,葛均波,钱菊英,史剑慧,王齐兵,牛玉宏,潘翠珍,樊冰,刘学波,张少衡,孙爱军,邹云增.急诊经冠状动脉自体骨髓单个核细胞移植治疗急性心肌梗死的临床研究[J].中国介入心脏病学杂志,2005,13(3):142-145. 被引量：29
  • 5王建安,谢小洁,孙勇,何红,蒋晨阳,周斌全,骆荣华,董.骨髓间质干细胞冠脉内移植治疗近期陈旧性心肌梗死伴心功能不全[J].中华急诊医学杂志,2005,14(12):996-999. 被引量：12
  • 6Schaefer A,et al.Impact of intracoronary bone marrow cell transfer on diast-olic Function in patients atter acute myocardial Infarction:results from the BO -OST trial[J].EurHeart J,2006,27:929-935.
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二级参考文献13

  • 1王建安,李长岭,樊友启,何红,孙勇.Allograftic bone marrow-derived mesenchymal stem cells transplanted into heart infarcted model of rabbit to renovate infarcted heart[J].Journal of Zhejiang University Science,2004,5(10):1279-1285. 被引量：14
  • 2Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarctedmyocardium. Nature, 2001,410:701-705.
  • 3Kocher AA, Schuster MD, Szabolcs MJ, et al. Neovascularization of ischemicmyocardium by human bone-marrow-derived angioblasts prevents cardiomyocyteapoptosis, reduces remodeling and improves cardiac function. Nat Med, 2001,7:430-436.
  • 4Tomita S, Mickle DA, Weisel RD, et al. Improved heart function with myogenesis andangiogenesis after autologous porcine bone marrow stromal cell transplantation. J Thorac Cardiovasc Surg, 2002,123:1132-1135.
  • 5Tang YL, Zhao Q, Zhang YC, et al. Autologous mesenchymal stem cell transplantationinduce VEGF and neovascularization in ischemic myocardium. Regulatory Peptiders, 2004,117:3-10.
  • 6Zhang S, Zhang P, Guo J, et al. Implantation of bone marrow cells upregulated expression of heat shock protein and VEGF in rat infarcted myocardium. Eur J Cardio Thorac Surg, 2004,25:188-195.
  • 7Britten MB, Abolmaali ND, Assmus B, et al. Infarct remodeling after intracoronaryprogenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI):mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation, 2003,108:2212-2218.
  • 8Chen SL, Fang WW, Ye F, et al. Effect on left ventricular function of intracoronarytransplantation of autologous bone marrow mesenchymal stem cell in patients with acutemyocardial infarction. Am J Cardiol, 2004,94:92-95.
  • 9Wollert KC, Meyer GP, Lotz J, et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet, 2004,364:141-148.
  • 10Goodell M, Brose K_Paradis G, Conner A, et al. Isolation and functional properties ofmurine hematopoietic stem cells that are replicating in vivo. J Exp Med, 1996,183:1797-1806.

共引文献38

同被引文献19

引证文献2

二级引证文献12

中医临床研究
2011年 第13期

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