布洛芬栓塞肛对小儿发烧降温疗效的研究

Antipyretic effect of embolization by Ibuprofen on fever in children

目的:观察布洛芬栓塞肛对小儿发烧降温疗效的影响。方法:323例高热患儿分别接受不同方式布洛芬治疗,即口服、灌肠和栓塞肛治疗;于治疗前及治疗后1h、2h和4h分别测定患儿体温,比较不同组的退热效果。结果:布洛芬口服组、灌肠组及栓塞肛组之间退热效果无明显差别(P>0.05);对灌肠组和栓塞肛组,布洛芬口服组1h退热程度低(P<0.05)。结论:布洛芬栓塞肛能有效治疗高热,适合临床治疗小儿高热。

Objective： To investigate the antipyretic effect of of embolization by Ibuprofen on fever in children. Methods：A total of 323 children with hyperpyrexia were assigned into 3 groups with different treatments by ibuprofen via embolization, oral administration and enema. Body temperatures were meas ured 1 h, 2 h and 4 h before and after therapy, and then the antipyretic effect were compared among three groups. Results： There was no significant difference in antipyretic effect among three groups （P〉0.05） Compared to enema group and embolization group, the antipyretic effect of oral administration group was lower at 1 h （P〈0.05）. Conclusions： Embolization by Ibuprofen is effective on fever, especially on fever in children.