2型糖尿病胃动力检测及西沙必利的治疗作用

THE EXAM OF DIABETIC GASTRIC MOTILITY AND CISAPRIDE′S TREATMENT ACTION

目的：为探讨糖尿病胃轻瘫（ＤＧＰ）的发病机理及西沙必利对ＤＧＰ的治疗作用。方法：应用ＷＤＬ－２０００ 型胃动力诊断仪对４０ 例２ 型糖尿病患者进行胃动力检测并与３０ 例健康人作对照。同时观察西沙必利治疗前后胃动力变化和血糖对胃动力的影响。结果：显示４０ 例糖尿病患者胃动力异常的血糖值与胃动力正常的血糖值有显著性差异（Ｐ＜ ０．００１）。胃动力异常检出率为７２．５％ ，与健康人相比具有显著性意义（Ｐ＜ ０．００５）。经西沙必利治疗后胃动力恢复正常率为７５．８％ ，且治疗前后的血糖值具有显著差异（Ｐ＜ ０．００１）。结论：观察说明胃动力异常可能为ＤＧＰ的发病机理。

Objective: In order to find out the cause of diabetic gastraparesis and to find out the Cisapride's treatment for DGP Methods: Motility treatment instrument of WDL 2000 type is used for checking gastric motility of 40 diabetic,who were compared with 30 healthy men At the same time, a observation of gastric motility change before and after the Cisapride's treatment is made and to observe how blood sugar affects gastric motility Results:The results show there is a clear difference between the blood sugar values of abnormal gastric motility patients and normal gastric motility patients ( P <0 001) The abnormal gastric motility exam rate is 72 5% , it has a notable meaning comparied with the healthy group ( P <0 005) The effective rate of the abnormal gastric motility among 28 Ⅱ type diabetic is 75 8% after Cisapride's threatment What is more, there is a clear difference the blood sugar values before and after treatment Conclusion:Abnormal gastric motility is likely to lead to DGP and the increase in blood sugar is key factor to cause gastris motility