摘要
对于乳腺癌患者可以通过Cell Search系统自动检测外周血中循环肿瘤细胞(CTC)数目。近期相关研究的结果提示对于晚期乳腺患者而言,CTC水平可以用来预测患者预后并早期预测对治疗的反应。但是在早期乳腺癌中CTC的预测价值并不确切。进一步了解CTC的生物学特性以及明确其作为预后预测的应用价值仍需要大型前瞻性临床研究结果的揭示。
Circulating tumor cells (CTCs) in breast cancer patients can be detected by Cell Search system. Results from recent studies suggested that CTCs level might serve as a prognostic marker and be used in the early assessment of therapeutic response in patients with metastatic breast cancer. However the role of CTCs in early stage breast cancer is not well established. Large prospective trials are needed to further understand its biological characteristics and to confirm its role as a predictive and prognostic marker.
出处
《国际肿瘤学杂志》
CAS
2011年第7期516-518,共3页
Journal of International Oncology
基金
首都医学发展科研基金重点项目(2009-2044)
关键词
乳腺肿瘤
肿瘤循环细胞
预测
Breast neoplasms
Neoplasm circulating cells
Forecasting