无创机械通气治疗COPD合并Ⅱ型呼吸衰竭疗效观察

The effectiveness of treatment with noninvasive mechanical ventilation on chronic obstructive pulmonary disease(COPD) complicated with type Ⅱ respiratory failure

目的探讨双水平正压无创机械通气治疗慢性阻塞性肺病合并Ⅱ型呼吸衰竭的治疗价值。方法将60例慢性阻塞性肺病合并Ⅱ型呼吸衰竭患者随机平行分为治疗组和对照组各30例。对照组给予抗感染、祛痰、平喘、呼吸兴奋剂、低浓度持续吸氧、雾化吸入及支持治疗,治疗组在对照组治疗的基础上给予无创机械通气模式,观察两组患者心率、呼吸频率、血气分析等指标。结果双水平正压无创机械通气对提高PaO_2和降低PaCO_2效果好,治疗组与对照组比较差异有统计学意义(P<0.05)。结论双水平正压无创机械通气对慢性阻塞性肺病合并Ⅱ型呼吸衰竭的治疗效果好,值得临床推广应用。

Objective To investigate the effectiveness of treatment with bilevel continuous airway pressure （BiPAP） ventilation on chronic obstructive pulmonary disease （COPD） complicated with type Ⅱ respiratory failure. Methods Sixty pa- tients with COPD complicated with type Ⅱ respiratory failure were assigned to BiPAP plus conventional therapy （ treatment group） or conventional therapy alone （ control group）. Control group received conventional management con - sisted of antibi- otics, apophlegmatic, anticonvulsive, respiratory stimulant and long - term low - dose oxygen therapy. In treatment group were treated with BiPAP ventilation in addition to above routine treatment, Observe two groups were breathing, heart rate, blood gas analysis, the length of hospitalization time for index. Results BiPAP no - ninvasive mechanical ventilation improve PaO2 and reduce PaCO2 effect were good, and hospitalization time was shortened, the treatment group compared with controls difference was statistically significant （ P 〈 O. 05 ）. Conclusion BiPAP no - ninvasive mechanical ventilation for chronic obstructive pulmonary disease combined type Ⅱ respiratory failure treatment effect was good, could shorten the length of hospitalization.