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Th17细胞与肺部疾病

Th17 cell and pulmonary diseases
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摘要 Th17细胞是新近发现的CD4T细胞亚群，困主要分泌白介素17而命名。白介素17是具有强大的招募中性粒细胞功能的前炎性细胞因子，可促进多种细胞释放炎性因子。Th17细胞在增强炎症反应的同时也提高了机体的防御能力，与肺部感染、气道慢性炎性疾病等密切相关。本文就此作一简要综述。 Th17 cell is a newly discovered subtype of CD4^＋ T cells. It can secret interleukin 17 （IL- 17） which determines its denomination. IL-17 is a kind of proinflammatory cytokine that can strongly recruit neutrophils and promote many kinds of cells to release inflammatory cytokines. Th17 cell can strenglhen inflammatory responses, and moreover, it enhances the bodyrs defense ability. It has a close relation with pulmonary infections, chronic inflammatory disorder of the airway and so on. This review nlakes a summing-up for it.
作者 孙燕 解卫平
机构地区 南京医科大学第一附属医院呼吸内科
出处 《国际呼吸杂志》 2011年第14期1086-1089,共4页 International Journal of Respiration
关键词 TH1 7细胞 白介素17 肺部感染 气道慢性炎症 Th1 7 cell Interleukin-17 Pulmonary infections Chronic inflammatory disorder of the airway
分类号 R563 [医药卫生—呼吸系统]
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参考文献21

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二级参考文献100

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国际呼吸杂志
2011年 第14期

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