兴城矿泉浴治疗强直性脊柱炎临床疗效评价

The evaluation of curative effect of treating the ankylosing spondylitis by Xingcheng mineral spring water baths

比较在改变病情药（DMARDs）基础上用矿泉和淡水浴治疗强直性脊柱炎（AS）的疗效。方法48例AS患者随机分为矿泉浴治疗试验组和淡水浴对照组，二组水温同为38～40℃，每次30分钟，每日1次，共60次；同时均口服柳磺毗陡（SASP）第1周0．5，每日3次，第2周起1．0，每日3次及甲氨喋呤（MTX）第1周5．0mg，第2周7．5mg，第3周10mg,第4周15mg，每周1次。治疗前后对腰背痛指数、晨僵时间、夜间痛计分、外周关节痛指数、胸廓扩张度、Schober试验、血沉（ESR）、C反应蛋白（CRP）、指地距、枕墙距及骰骼关节X线改变等指标进行评价并对比分析。结果试验组总有效率（87．50％）明显高于对照组（56．25％，P＜0．05），尤其在改善夜间痛、外周关节痛、枕墙距、指地距、腰背痛、CRP及缩短晨但时间方面优于对照组（P＜0．05）。结论兴城矿泉浴在治疗AS时可对DMARDs产生协同作用。疗效优于对照组。

Objective To be clinical effectiveness in ankylosising spondylitis(AS) patients with 60 times mineral spring bathstherapy, compared with fresh water baths therapy. On the basis of methotrexate(MTX) plus sulfasalazine(SASP).Methods 48 cases with AS were randomh divided into mineral spring water sroup and fresh water group, the temperature of the water is 30 ～ 40℃, a time each day, 30 minutcs each time, and oral MTX plus SASP. Before and aftertreatment, the changes in lambar pain, morning stiff time, peripheral joint pain, thoracic expansion, schober test, ESR,CRP, pain in night and radioactive sacroiliitis were analysed respectively.Results Thc treatment group was superior to the control group in total efficacy rate, especially in bettering morningstiff time, peripheral joint pain, occipioto - wall gap, fingernail - land, pain in night and CRP.Conclusion Xingcheng mineral spring baths can play joint role with DMARDS in treating the patients with AS.