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基质金属蛋白酶与类风湿性关节炎骨侵蚀关系的研究进展 被引量:9

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摘要 类风湿性关节炎(RA)的发病机理尚不清楚,现在普遍认为是多基因和环境因素共同诱发病理性自身免疫性炎症反应,主要表现为破坏性多关节炎和不同的关节外炎症病变。研究发现炎性因子IL-1、IL-17、TNF-α、基质金属蛋白酶(MMPs)等在RA的关节破坏中发挥重要作用,本文就MMPs与RA骨侵蚀的研究进展进行综述。
出处 《内科》 2011年第4期342-345,共4页 Internal Medicine
基金 广西壮族自治区卫生厅科研基金(220103383)
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