思密达治疗婴幼儿腹泻86例临床实验

Efficacy of oral smecta in the treatment of infantile diarrhea

目的 :评价思密达治疗婴幼儿腹泻的疗效。方法 :思密达口服治疗婴幼儿腹泻。病例为儿科门诊病人 ,年龄 2 - 6 0个月 ,疗程在 3天内 ,症状为排稀水样便。就诊前未服用过本组实验药物的腹泻病人 173例 ,随机分二组 ,分别给予服思密达或黄连素片。结果 :治疗组平均疗程 2 93天 ,对照组 4 4 7天 ,x2 =4 39,p <0 0 5。思密达总有效率 94 1% ,对照组 79 3% ,x2 =13 8,p <0 0 1。两组结果比较 ,差别均有显著意义。结论 :思密达治疗婴幼儿腹泻在疗程与疗效上与对照组相比有显著差异。

OBJECTIVE:The aim of this study was to evaluate the efficacy of oral smecta in young children with infantile diarrhea. METHODS:One hundred and seventy three consecutive young children who suffered fron infantile diarrhea had been randomly allocated into two gronps.The patients were randomly assigned to either treatment group (receiving oral smecta).RESULTS:In smecta group and berberinum group,cure rates were 94 1% and 79 3% respectively(x 2=13 8,p<0 01).There was significant difference between two groups in mean recovery time(2 93 day in smecta group;4 47 days in control group).CONCLUSION:Considering the effectiveness,oral smecta may be necessary for treating infantile diarrhea in young children.