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透明质酸的黏度及相对分子质量 被引量:1

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摘要 用沉降平衡法确定低相对分子质量(Mr=1×104~7.2×104)及高相对分子质量(Mr=3.1×105~1.5×106)透明质酸(HA)的特性黏度([η])和Mr。两种HA,其[η]对Mr的双对数图显示出不同的线性。低Mr的HA,[η]=3.0×10-6×Mr 1.20,对高Mr的HA来说,[η]=5.7×10-4×Mr 0.76。两线交叉点的HA Mr大约为1.5×105。Mr小于2.1×104的HA,其流变性(比浓黏度)与浓度无关;而大于5.7×104的HA,其流变性(比浓黏度)随浓度的增大而增加。
出处 《食品与药品》 CAS 2011年第7期301-303,共3页 Food and Drug
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  • 1Varga L. JBiol Chem, 1955, 217: 615-658.
  • 2Laurent T C, Ryan M, Pietruszkiewica A. Biochim Biophys Acta, 1960. 42:476-485.
  • 3Preston B N, Davies M, Ogston A G. Biochem J, 1965, 96:449--474.
  • 4Swarm D A. Biochim Biophys Acta, 1968, 156:17-30.
  • 5Cleland R L, Wang J L. Biopolymers, 1970,9: 799-810.
  • 6ShimadaE,MatsumuraG.生化学(inJapanese),1972,44:655.
  • 7ShimadaE,YamaguchiLMatsumuraG.JBiochem,1972,71:9-16.
  • 8Ohya T, Kaneko Y. Biochim Biophys Acta, 1970,198: 607-609.
  • 9Tolksdorf S, McCrcady M H, McCullagh D R, et al. J Lab Clin Med, 1949, 34: 74-89.
  • 10Radhakrishnomurthy B, Dalferes E R, Berenson G S. Anal Biochem, 1966, 17: 545-550.

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  • 1Lin W, Shuster S, Howard HI, et al. Patterns of hyaluro- nan staining are modified by fixation techniques [ J ]. J Histochem Cytochem, 1997,45 ( 8 ) : 1157-1163.
  • 2Ohtani T, Memezawa A, Okuyama R, et al. Increased hy- aluronan production and decreased E-Cadherin expression by cytokine-stimulated keratinocytes lead to spongiosis for- mation [ J ]. J Invest Dermatol,2009,129 (6) : 1412-1420.
  • 3Sandjeu Y, Haftek M. Desmosealin and other components of the epidermal extracellular matrix [ J ]. J Physiol Phar- macol, 2009, ( 60 suppl 4 ) : 23-30.
  • 4Sakai S, Yasuda R, Sayo T, et al. Hyaluronan exists in the normal stratum corneum [ J ]. J Invest Dermatol, 2000, 114(6) :1184-1187.
  • 5Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging [ J] . Dermatoendocri- nol, 2012,4(3): 253-258.
  • 6Necas J, Bartosikova L, Brauner P, et al. Hyaluronic acid (hyaluronan) : a review [ J ]. Vet Med, 2008,53 ( 8 ) : 397-411.
  • 7李腾飞.低分子量透明质酸超声化学制备的基础及实验研究[D].四川:重庆大学,2011.
  • 8Wu Y. Preparation of low-molecular-weight hyaluronic acid by ozone treatment [ J ]. Carbohydr. Polym,2012,89 (2) :709-712.
  • 9陈坚,堵国成,王淼,等.一种在发酵过程中添加透明质酸酶生产小分子量透明质酸的方法:中国,专利号200810123395[P].2008-05-26.
  • 10惠觅宙,刘珊,吴书音,等.一种重组长效透明质酸酶、其编码基因、生产方法及应用:中国,专利号201310325056.x[P].2013-07-30.

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