CT导引下冷循环射频消融术治疗老年人肺恶性肿瘤的临床应用

The study on CT--guided cool--trip radiofrequency ablation in the treatment for elderly puhnonary malignancy

目的：探讨在CT引导下冷循环射频消融（RFA）治疗老年患者肺部恶性肿瘤的临床疗效及安全性。方法：CT引导下对48例经病理学确诊肺部恶性肿瘤老年患者的53个瘤体进行RFA治疗，对其中8个瘤体进行2次重复消融。所有患者术后1个月、3～6个月后行胸部CT检查评价肿瘤疗效。结果；48例老年患者均顺利完成RFA治疗。全部患者无严重并发症，无围手术期死亡。肿瘤疗效评估显示：CR3个，PR34个，NC12个，PD4个，总有效率（CR＋PR）为69．8％。结论：CT引导下经皮穿刺射频消融肺恶性肿瘤的疗效确切，创伤小，并发症少，安全性高，是治疗老年人肺部恶性肿瘤的较为理想的微创治疗方法。

Objective To investigate the clinical efficacy and safety of CT--guided cool--trip radiofrequency ablation （RFA） in the treatment for elder- ly pulmonary malignancy. Methods With pathologically diagnosed, CT-guided RFA was performed in 48 patients carrying a total of 53 malignant pulmo- nary lesions. Of the 53 lesions, two times of overlapping RFA was done on 8. 1 month and 3~6 months after the procedure, postoperative checkup with CT scanning was conducted in all patients to evaluate therapeutic resuhs. Results CT--guided RFA was successfully accomplished in all patients. During the operation, no serious complications, perioperative deaths occurred. Evaluation of curative effect showed that CR was obtained in 3 cases, PR in 34 ca- ses, NC in 12 cases and PD in 4 cases. The total effective rate （CR＋PR） was 69.8%. Conclusion In the treatment for elderly pulmonary malignancy, CT --guided radiofrequency ablation is an appropriate, effective, safe technique with less trauma and complications.