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Akirin1基因在肌肉发生中的作用

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摘要 Akirin1是2008年新发现的基因,其编码一个极为保守的核蛋白。研究表明,Akirin1在肌肉形成与重生中有重要作用,在C2C12细胞中的过表达能够促进生肌分化。Akirin1也能参与果蝇和小鼠的先天免疫反应,果蝇S2细胞缺失该基因后抵抗革兰氏阴性菌侵染的能力下降。尽管对Akirin1的研究日益增多,但是该基因的作用机制及相关表达调控尚未完全阐明。本文综述目前国内外对Akirin1的研究进展。
作者 汪海鹏 原雪莹 倪华
机构地区 东北农业大学生命科学学院
出处 《黑龙江动物繁殖》 2011年第4期11-14,共4页 Heilongjiang journal of animal reproduction
关键词 Akirin1 MYOSTATIN 生肌过程 肌肉重生
分类号 S814.3 [农业科学—畜牧学]
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参考文献11

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二级参考文献15

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共引文献5

黑龙江动物繁殖
2011年 第4期

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