黄浦区美沙酮社区药物维持治疗依从性及影响因素分析

目的:研究海洛因成瘾者美沙酮维持治疗(MMT)的依从性及其影响因素,为提高其长期治疗的依从性提供信息依据。方法:采用流行病学队列研究方法,收集黄浦区美沙酮社区药物维持治疗门诊223例海洛因成瘾者的社会人口学特征、滥用药物史及美沙酮治疗及脱失情况资料,进行统计描述、单因素、多因素分析。结果:研究对象分布以男性、31～50岁、单身、初中文化程度、没有工作、缺乏家庭关爱者为主;平均吸毒年份为10.30±4.59年,每日吸食海洛因1.0～2.0克者占57.0%,注射吸毒者占73.1%。统计分析显示入组年龄、与家人关系、既往每天海洛因吸食数量、美沙酮服用天数是MMT依从性的影响因素。结论:加强海洛因成瘾者MMT的依从性,减少脱失,家庭和社会的支持鼓励很重要。

Objective：Learn about compliance and determinant among heroin addicts who are willing to receive Methadone Maintenance Treatment（MMT） so as to provide information for improving adherence. Methods ： Demographic characteristics, drug abuse and MMT information of 223 heroin addicts in Huangpu District were col- lected for analysis. Results：Distribution of subjects was male ,31 to 50 years old, single, junior middle school education, no job and lack of family care. The mean duration of drug use was 10.30：1：4.59 years. The rate of intaking heroin 1.0 to 2.0g one day before they received MMT was 57.0%. The majority （73.1%） were injection drug users. Statistics indicated that enroUed age, relations with their families, dose of heroin per day and methadone used days were related to compliance. Conclusion： It is important that family and community should support and encourage heroin addicts.