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甲基泼尼松龙冲击治疗Graves眼病67例疗效观察

The treatment of methylprednisolone on 67 GO patients
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摘要 目的:探讨甲基泼尼松龙对Graves眼病进行冲击治疗的疗效。方法:纳入67例患者。实验组36例,给予甲基泼尼松龙第1d500mg,2-8d80mg,9-15d40mg,第16日后改为口服泼尼松;对照组31例,给予甲基泼尼松龙1-3d500mg,第4日开始口服泼尼松。结果:2个月后实验组患者复视和眼球活动障碍有更大程度的恢复,且副作用更少,p<0.05。结论:不同冲击方法对Graves眼病的治疗显示,给予甲基泼尼松龙首次大剂量后改为中剂量治疗效果好且副作用少。 Objective:To investigate the effect of methylprednisolone (MPSL) on Graves'ophthalmopathy (CO). Methods:67 GO patients were involved ,36 in experimental group ( MPSL 1 d 500rag,2 - 8d 80rag,9 - 15d 40mg) ;31 in control group, ( MPSL 1 - 3d 500mg). Results:Experimental group had better recovery of diplopia and eyeball activities, p 〈 0.05. Conclusion:The treatment of high dose on first day followed by moderate dose has better effect.
出处 《医学信息(中旬刊)》 2011年第7期3080-3081,共2页 Medical Information Operations Sciences Fascicule
关键词 甲基泼尼松龙 GRAVES眼病 疗效 MPSL GO Effect
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