毛细支气管炎与哮喘相关性研究进展

Research progress on Assosiation of bronchitis with asthma

支气管哮喘是由多种细胞(如嗜酸性粒细胞、肥大细胞和T淋巴细胞、中性粒细胞等)和细胞组分多参与的气道慢性炎症行疾病。越来越受到临床工作者的重视。毛细支气管炎是一种主要由呼吸道合胞病毒引起的婴幼儿较常见的下呼吸道感染,患儿毛细支气管炎后易于发生哮喘,通过长期的临床随访发现22%-55%的毛细支气管炎患儿患哮喘,数值明显高于正常儿童。研究显示毛细支气管炎发展成为哮喘与遗传、免疫、感染、环境污染等许多因素有关。笔者从遗传、免疫、感染等方面阐述毛细支气管炎与哮喘相关性研究。

The bronchus asthma is is composed with many kinds of cells（ such as eosinophils, mast cells and TLymphocytes, neutrophils, etc ）, it also the disease which components in chronic inflammation of the airway. More and more get the attention of the clinical workers. Capillary bronchitis is a main by respiratory syncytial vires causes the infant of the more common lower respiratory tract infection. Children capillary who has bronchitis prone are easy to catch asthma. Through the long - term clinical follow - up found that 22% - 55 % of the capillary children with asthma bronchitis, the numerical obviously higher than normal children. Research shows that the capillary bronchitis development as an asthma and genetic, immune, infection, the environmental pollution and so on many factors. This article reviews the correlation about bronchitis and asthma from genetic,immune,infection and so on.