东方人耳部瘢痕疙瘩综合治疗方法探讨

Effective integrated therapy for ear keloids in the Oriental

目的 探讨东方人耳部瘢痕疙瘩综合治疗的有效性.方法 采用手术切除瘢痕疙瘩,直接缝合或转移皮瓣修复,于手术切除后早期（24 h内）联合X线或电子线局部放射治疗,每日1次,共3～5次,7 d拆线后局部注射激素类抗瘢痕药物治疗,每2周1次,视切口愈合情况逐渐减量停药.结果 共治疗48例,除由于各种原凶失访12例外,36例随访1～3年,其中治愈30例（83.3%）,显效4例（11.1%）,总有效率94.4%.结论 手术切除病损,联合早期局部放射治疗及拆线时局部定期注射激素类抗瘢痕药物,是综合治疗耳部瘢痕疙瘩防止复发的有效方法.

Objective To explore the effective measurements of integrated therapy for the ear keloids in the Oriental. Methods Surgical excision was performed for keloid, and the cut then sutured directly or with flap transfer. At early stage of surgery （within 24 hours）, X-ray or electron-ray radiotherapy was used for 3-5 times once daily; and steroids injected after cutting lines at 7th day every two weeks and gradually ended. Results A total of 48 patients were treated, and followed, in which 12 patients were lost of follow-up. The total effective rate was 94. 4 % based on the data of follow-up in 36 patients for 1-3 years. Therefore, the curation rate was 83. 3 % （30 cases） and effective rate 11. 1 % （4 cases）. Conclusions Surgical cutting combined with early radiotherapy and steroids injection is the effective integrated therapy for the ear keloids in the Oriental.