拓展眼底自身荧光临床研究的广度和深度，提升其应用研究水平

Explore the breadth and depth of clinical research and applications of fundus autofluorescence

眼底自身荧光（FAF）主要来源于视网膜色素上皮（RPE）细胞内堆积的代谢产物脂褐质，是活体条件下评价RPE活性与形态学改变的重要检测工具。作为一种无损伤、可重复、简便快捷的检测手段，FAF结合其他眼底形态与功能检测方法，可从RPE结构和功能变化的角度为部分常见眼底疾病提供辅助诊断依据。在逐步认识各种眼底疾病FAF表现特征的同时，对FAF结果量化分析，充分利用FAF以及其他检测手段的优势互补，从发生机制上加深眼底疾病FAF表现特征的认识，积极拓展其合理和独有的临床应用领域，将有助于对眼底疾病内在病理机制获得更新的认识，指导获得更为合理有效的诊疗经过。

Fundus autofluorescence （FAF） relies primarily on the presence of accumulated lipofuscin in the retinal pigment epithelium （PRE） cells. It has emerged as a valuable tool to detect and evaluate the viability and structural changes of the RPE in live. As a nowinvasive, repeatable, simple and efficient means of detection, FAF imaging can provide information of RPE structure and function to assistant the diagnosis of many retinal diseases with other conventional fundus imaging technologies. With quantitative analysis and complementary analysis with other fundus imaging technologies, the FAF features of different retinal diseases will be further understood. This knowledge will not only extend the reasonable and unique clinical applications of FAF, but also will contribute to the understanding the pathogenesis and improving the treatment of many retinal diseases.