妊娠合并梅毒56例分析

Clinical analysis on 56 cases of syphilis-associated pregnancy

目的了解妊娠合并梅毒的发病情况。方法回顾性调查分析了2009年12月8日~2011年2月28日在我院住院时发现妊娠合并梅毒56例的临床资料。结果妊娠足月胎膜早破13例,临产15例,前置胎盘大出血5例,妊娠足月要求选时剖宫产3例,因妊娠期肝内胆汁瘀积症入院治疗3例,胎膜早破保胎6例,妊娠期高血压5例,妊娠剧吐6例。年龄18~43岁,初产妇39例,经产妇17例。未婚8例,已婚48例,配偶曾患梅毒8例。3例分别有先兆流产、死胎史,6例有多次流产、死胎、胎儿水肿引产、死产、早产（早产儿死亡）等不良生育史。结论重视婚前和孕前检查,孕早期或第一次产前检查,必须加强孕期梅毒筛查,早期诊断及治疗,消除先天梅毒。

Objective To analyse the manifestation of pregnancy with syphilis infection.Methods The clinical data of 56 pregnancy cases with syphilis,who hospitalized in our hospital in December 8th,2009～February 28,2011,were surveied and analysed retrospectively.Results Premature rupture of membranes in 13 cases with full-term pregnancy,parturient in 15 cases,placenta previa with large hemorrhage in 5 cases,full-term pregnancy in 3 cases,pregnancy with intrahepatic bile stagnation in 3 cases,prevent miscarriage with premature rupture of membrane in 6 cases,hypertension in 5 cases,hyperemesis gravidarum in 6 cases.Conclusion Attention to premarital and pregnant examination.The pregnancy syphilis screening in the early stages of pregnancy or first antenatal examination must be executed.