少数民族地区孕妇弓形虫感染免疫学检测研究

Study on the immunology detecting Toxoplasma infection of pregnant women in minority nationality regions

目的:调查少数民族地区弓形虫感染状况及其对胎儿的影响。方法:用酶联免疫吸附法(ELISA)检测孕妇血清弓形虫循环抗原(CAg)、IgM及IgG抗体水平。结果:86例病理妊娠的孕产妇中,3项指标阳性40例,阳性率为46.5%,血清中CAg阳性7例,阳性率为8.13%;IgM阳性12例,阳性率为13.95%;IgG阳性21例,阳性率为24.41%。结论:弓形虫感染对胎儿有较大危害,是引起胎儿流产、死胎及畸形的主要原因之一。少数民族地区不同民族孕产妇弓形虫感染率比较差异无统计学意义,孕产妇弓形虫感染率与猫、犬接触史明显相关。基层地区加大孕妇弓形虫感染检测对民族优生优育有较大帮助。

Objective：To investigate the infection status of Toxoplasma in the minority nationality regions and its infection on the infants.Methods：By enzyme-linked immunosorbent assay（ELISA）,the level of CAg,IgM and IgG were detected in the blood of pregnant women.Results：In 86 cases of pathological pregnancy,the positive rate of CAg,IgM and IgG was 46.5%（40 cases）,the positive rate of CAg was 8.13%（7 cases）,the positive rate of IgM was 13.95%（12 cases）,the positive rate of IgG was 24.41%（21 cases）.Conclusion：Toxoplasma infection harms the infants health and is a main cause of abortion,stillborn foetus and malformation.There are no significant differences among nationalities about the infection rate of Toxoplasma,but the infection rate of Toxoplasma is significantly related to any history of contacting with cats,dogs.