早产儿支气管肺发育不良危险因素分析

Risk factors of broncho-pulmonary dysplasia in premature infants

目的:探讨早产儿支气管肺发育不良(BPD)的危险因素及预防措施。方法:回顾性分析住院28天以上的早产儿102例,探讨BPD与孕周、出生体重、窒息、吸氧、母亲妊娠并发症、宫内感染性肺炎及机械通气等因素的关系。结果:102例早产儿中BPD者21例,BPD发生率为20.59%(21/102),孕周、出生体重、吸氧浓度>40%的持续时间、宫内感染性肺炎、机械通气及PDA与BPD的发生有关。且吸氧浓度越高,机械通气时间越长,BPD的发生率越高。结论:BPD的发生与孕周、出生体重、吸氧浓度>40%的持续时间、宫内感染性肺炎、机械通气及PDA等因素有关。Logistic回归分析显示宫内感染性肺炎是BPD的独立危险因素。

Objective：To investigate the risk factors of broncho-pulmonary dysplasia（BPD） in premature infants and its prevention and treatmentMethods：A retrospective study was performed in 102 premature infants with hospitalized more than 28 days.The relationship among BPD and GA,BWT,asphyxia,oxygen inhalation,pregnant complications,infectious pneumonia and mechanical ventilation were analyzed.Results：The incidence of BPD was 20.59%（21/102）.GA,BWT,the time of inhalation of high concentrations of oxygen,infectious pneumonia,mechanical ventilation and PDA were related to BPD.Conclusion：Logistic regression analysis show that infectious pneumonia is independent risk factor of BPD.