肾茶对尿路结石的治疗作用

Effect of Clerodendranthus Spicatus on Urinary Calculus

目的 评价肾茶治疗尿路结石的疗效。 方法 小鼠随机分为肾茶治疗组和对照组。家兔做为输尿管动作电位改变的动物模型。临床上观察６６ 例尿路结石患者使用肾茶治疗疗效，６０ 例患者作为对照组。 结果 肾茶在动物急性毒性试验中表明无毒性，家兔输尿管动作电位的频率和幅度增加，有排石利尿、抗菌止血作用。肾茶治疗组痊愈率（８４％ ）和总有效率与安慰剂组比较差异有非常显著性意义（Ｐ＜ ０．０１）。 结论 肾茶是一种治疗尿路结石的无毒副作用的药物。

To investigate the mechanism and treatment role of clerodendranthus spicatus(CS) on urinary calculus and hematuria \ Methods\ The mice were randomly divided for detecting the LD\-\{50\} and bleeding time and the rabbit were examined for potential change in ureter when taking CS Hematuria of urinary calculus was treated in 66 patients with CS,60 patients as control \ Results\ CS has not toxic effects on animal in acute toxicity tests The rabbit ureteric action potential in rate and amplitude were increased CS may be a drug of diuresis and expel stones,antibacterial,hemostatic There was significant difference in the clinical cure rates(84%) and effective rate in two groups(P<0 01) \ Conclusion\ The results demonstrated that CS is an effective drug of treating hematuria of urinary calculus with few side effects \;