摘要
胰岛素样生长因子(insulin-like growth factor,IGF)系统由具有特定功能的配体、受体和结合蛋白组成,在正常生理活动中有极为重要的意义。现已发现,许多疾病如糖尿病、胰岛素抵抗、内分泌紊乱、癌症、营养不良和多囊卵巢综合征(polycystic ovary syndrome,PCOS)等与IGF系统密切相关。体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)助孕治疗中,多囊卵巢综合征病人易发生卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS),IGF系统在OHSS的发生中起一定的作用。
The insulin-like growth factor（IGF） system is ubiquitous and plays important role in every tissue of the body.There are now numerous examples o fdiseases such as polycystic ovary syndrome,diabetes,cancer and malnutrition in which the IGF system is a major player.the IGF system plays a role in ovarian hyperstimulation syndrome（OHSS） in vitro fertilization and embryo transfer（IVF-ET）.
出处
《内蒙古医学院学报》
2011年第3期256-259,共4页
Acta Academiae Medicinae Neimongol
基金
内蒙古自然科学基金项目(Kjto9115)
关键词
胰岛素样生长因子
多囊卵巢综合征
体外受精-胚胎移植
卵巢过度刺激综合征
Insulin-like growth factor system
polycystic ovary syndrome
in vitro fertilization and embryo transfer
ovarian hyperstimulation syndrome
