术中快速冰冻切片在136例腮腺肿瘤中的诊断价值

Diagnostic value of intraoperative frozen section for parotid gland tumours in 136 cases

目的通过分析和比较腮腺肿瘤术中快速冰冻切片和术后最终病理诊断结果,评估术中快速冰冻切片在腮腺肿瘤诊断中的意义。方法对136例腮腺肿瘤行术中快速冰冻切片诊断肿瘤的性质与最终病理诊断进行对比分析。结果 136例腮腺肿瘤中经最终病理诊断,良性肿瘤97例,恶性39例;快速冰冻切片诊断鉴别出恶性肿瘤的准确率为95.6%。39例恶性肿瘤中最终病理诊断为恶性程度较高类型肿瘤12例,经快速冰冻切片诊断的准确率为76.9%。结论快速冰冻切片在腮腺手术中可提供一种快速准确诊断良、恶性肿瘤的的手段,并为临床判断腮腺恶性肿瘤恶性程度提供一定的参考,应作为腮腺手术术中的常规检查手段。

Objective To evaluate the diagnostic value of intraoperative frozen section（FS） for parotid gland tumours via comparing FS with final histopathologic diagnosis.Methods The intraoperative FS results of 136 patients with parotid tumors were analyzed and compared with their final histopathologic diagnosis.Results Of all the 136 cases,97 were diagnosed as benign tumors of parotid gland and 39 as malignant with the final histopathology.The accuracy of intraoperative FS in detecting malignant tumors was 95.6%.In 12 of the 39 cases with malignant tumors of high pathological grade confirmed by final histopathologic diagnosis,the accuracy of intraoperative FS was 76.9%.Conclusion Intraoperative frozen section may provide accurate information on detecting malignant parotid tumors and useful information on picking out high-grade carcinoma rapidly.The use of intraoperative FS in parotid surgery is recommended.