离子型聚丙烯纤维对病毒的吸附作用研究

Adsorption of virus onto ionic surfactants of polypropylene fibers

目的 研究新型离子型聚丙烯纤维以防止病毒感染.方法 构建四种离子型表面活性聚丙烯纤维,与表达GFP的重组腺病毒分别相互作用,通过观察GFP的表达和病毒六邻体壳粒基因的表达来判断纤维对病毒的吸附能力.结果 四种纤维对腺病毒具有一定的吸附或灭活能力.金属离子纤维和两性离子聚丙烯纤维具有更好的灭活病毒能力.结论 提示金属离子纤维和两性离子聚丙烯纤维可以作为实验室防护装备的原材料.

Objective To provide better laboratory protection material in virology lab to prevent laboratory accident infection. Methods The four kinds of ionic polypropylene fibers were constructed and interact with recombinant adenovirus expressing GFP. Both the GFP expression and hexon gene expression of recombiant adenovirus were used to evaluate absorb ability of fibers. Results Both the amphoteric and iron ionic polypropylene fibers have certain adsorption or inactivated ability to virus in S min, the other two fibers decreased the growth within 20 min. Conclusion Both the amphoteric and iron ionic polypropylene fibers can be used as laboratory protection material in virology lab.