肝脏、胆囊、胆管、胰腺癌前病变的诊断与治疗

The Diagnosis and Treatment of Liver,Gallbladder,Bile Duct,Pancreatic Cancer Precancerous Lesions

目的:探讨肝脏、胆囊、胆管、胰腺的癌前病变的诊断方法与治疗措施。方法:对159例肝脏、胆囊、胆管、胰腺癌前病变患者的临床病理及诊治、预后进行回顾性分析,观察其病变的病理特点,明确其病变的机制,采取合理的治疗方法,并进行1、3、5年的随访,观察其存活率。结果:98例肝脏癌前病变患者,1、3、5年存活率分别为75.5%、45.9%、20.4%;24例胆囊癌前病变患者,1、3、5年存活率分别为70.5%、37.5%、12.5%;胆管癌前病变10例,1、3、5年存活率分别为70%、40%、20%;胰腺癌前病变27例,1、3、5年存活率分别为66.7%、33.3%、7.4%。结论:肝脏、胆囊、胆管、胰腺癌前病变的早期诊断、早期治疗对患者预后和提高存活率具有重要意义,因此,应加强对癌前病变的认识,提高诊断率,争取给予早期治疗,以改善患者预后,提高疗效和生存率。

Objective： To discusse the precancerous lesions of the diagnosis and Ucatmentthe of the liver, gallbladder, bile duct and pancreas. Methods：Choose the 159 cases who have liver, gallbladder, bile duct, pancreatic precancerous lesions were admired our rooms of clinical pathology and treatment and prognosis were analyzed retrospectively, Observed the characteristics Pathological lesions, to clarify its mechanisms of disease, take reasonable treatment,and for 1 year, 3 years, 5 years of follow-up to observe the survival rate.Results：98 cases of liver precancerous lesious, l, 3, 5-year survival rates were 75.5%, 45.9%, 20.4%;24 cases of gallbladder disease in patients before, 1, 3, 5-year survival rates were 70.5%, 37.5%, 12.5%; Precancerous lesions of 10 cases of cholangiocarcinoma, t. 3, 5-year survival rates were 70%, 40~/0, 20%; Precancerous lesions of 27 cases of pancreatic cancer, I year, 3 years, 5 years surcival rates were 66.7%, 33.3%, 7.4%. Conclusions：The early diagnosis, early a＇eatment of the Liver, gallbladder, bile duct, pancreatic precancerous lesions is very improtant, therefore,we should enhance the understanding of precancerous lesions and improve the diagnostic rate, and strive to give early treatraem to improve the prognosis of patients, improve the efficacy and survival.