儿童血铅水平与5种微量元素相互关系的研究分析

The Research and Analysis of the Relationship between Children's Blood Lead Levels and 5 Trace Elements

目的:探讨儿童血铅水平与血液中锌、铁、钙、镁、铜5种微量元素的相互关系。方法:根据污染程度的不同随机整群分层选取我县8个不同区域的4897例3～12岁儿童的血样进行(博晖BH5100T型)原子吸收光谱仪分析,监测血液中铅、锌、铁、钙、镁、铜6种微量元素的含量,探讨儿童血铅水平与其他5中微量元素之间的相互关系。结果:4897例受检儿童的血铅水平在0.024～0.267mg/L之间,几何均值为0.105mg/L,铅中毒的发生率为28.7%;线性回归分析,锌、铁的标准回归系数最大,分别为0.073和0.054,与儿童的血铅水平具有显著差异(P<0.01);用双因素方差分析血铅与血锌、血铁水平呈负相关。结论:儿童血铅水平高可导致血锌、血铁水平下降,铅中毒时可用锌和铁解铅毒.

Objective： To investigate the the relationship between Children＇s blood lead levels and 5 trace elements.Methods：According to the different degree of pollution stratified random selection of 8 different areas of the county＇s 4,897 cases of children aged 3 to 12 blood samples （Bo Hui BH5100T type） atomic absorption spectrometer analysis,monitoring of blood lead,zinc,iron,calcium,Magaesium, copper content of 6 trace elements, blood lead levels in children and the other 5 in the relationship between trace elements.Results：The blood lead levels of 4897 ehild^n in subjects is between 0.024-0.267mg/L,the Geometric mean is 0.105 mg/L, the incidence of lead poisonin is 28.7%; The linear regression analysis of the levers of Zn and Fe is 0.073 and 0,054. And children＇s blood lead levels were significantly different （P〈0.0l）,Two-factor analysis of variance with blood lead and serum zinc, serum iron level was negatively correlated.Conclusions：Children with high blood lead levels can lead to blood zinc,blood iron levels drop,lead poisoning, zinc and iron in solution is available when lead poisoning.