冠心病心力衰竭患者血浆B型尿钠肽水平与血清超敏C反应蛋白水平的相关性分析

The recativity analysis between B-type natriuretic and high sensitive C-reactive protein level in heart failure patients with coronary artery disease

目的 探讨冠心病患者心力衰竭时血浆B型尿钠肽（BNP）及超敏C反应蛋白（hs-CRP）水平的变化,以及两者的相关性分析.方法 测定74例冠心病心力衰竭患者和35例同期健康体检者比较两组血浆BNP水平和血清hs-CRP水平.结果 冠心病心力衰竭患者血浆BNP及超敏C反应蛋白水平均明显高于对照组（P〈0.01）,且BNP及hs-CRP正相关.结论 冠心病患者心力衰竭时BNP及hs-CRP水平增高,BNP与hs-CRP两者存在一定的相关性.

Objective To elucidate the change and relationship between B - type natriuretic （BNP） and high sensitive C - reactive protein （hs - CRP）level when there is heart failure in patients with coronary artery disease.-Method compare BNP level and Hs - CRP level of blood plasma from measuring 74 patients with coronary artery disease or heart failure and 35 ：normal individuals with the same period. Outcome： The BNP level and high sensitive C - reactive protein level of the patients with coronary artery disease or heart failure are significantly higher than those of normal individuals. Moreover, the BNP level and hs - CRP level show positive correlation. Conclusion The BNP level and hs - CRP level increase while there is heart failure in patients with coronary artery disease.