成人巨幼细胞性贫血48例病因分析

Etiological analysis of 48 adults with megaloblastic anema

目的探讨成人巨幼细胞性贫血的病因。方法回顾性分析48例成人巨幼细胞性贫血的临床资料。结果成人巨幼细胞性贫血以老年患者居多占（34／48）70．8％，其病因以消化道疾病占绝大多数，为85．4％（41／48），其中慢性胃炎9例占18．8％，消化道憩室8例占16．7％，十二指肠溃疡和胃全切除各4例为8．3％，食管裂孔疝和胃溃疡各3例为6．3％，胃息肉、口腔病变、空肠切除各2例为4．1％，Crohn病、节段性回肠炎、小肠淋巴瘤、慢性结肠炎各1例为2．O％。非胃肠道病变仅7例占14．6％。结论巨幼细胞性贫血以老年人占多数，而且以消化系统疾病为主。

Objective To explore guide adult giant young cell anemia cause. Methods Retrospective analysis 48 cases adult giant young cell anemia clinical data. Results The adult giant young cell anemia majority in elderly patients of（34/48） 70.8% ,its cause a majority in gastrointestinal diseases（41/48 ） for 85.4% ,among them 9 cases of chronic gastritis （ 18.8% ） Gastrointestinal diverticula 8 cases, the digestive tract of release, duodenal ulcer and gastric 16.7% each 4 cases total resection for 8.3, hiatal hernia and gastric ulcer each 3 cases of gastric polyps, oral 6.3% lesions,jejunum resection 2 cases 4.1 percent of all the rest a few Crohn, Crohn＇s disease, intestinal lymphoma,chronic colitis each 1 case of 2.0%. The gastrointestinal lesions accounted for only 14. 6% cases. Conclusion Giant young cell anemia majority witla old people, and to the digestive system disease primarily