DL-苯丙氨酸酶法拆分

Enzymatic Resolution of DL phenylalanine with Hog Renal Acylase

ＤＬ－苯丙氨酸的拆分是以Ｎ－乙酰－ＤＬ－苯丙氨酸铵为起始原料，经猪肾酰化酶不对称水解作用，再经离子交换色谱分离，减压浓缩得到Ｌ－苯丙氨酸和Ｎ－乙酰－Ｄ－苯丙氨酸结晶。

The resolution of DL phenylalanine with asymmetric hydrolysis of pig renal acylase has been developed by using ammonium N Acetyl DL phenylalanate as a starting material. In this procedure, L phenylalanine and N Acetyl D phenylalanine were separated by Ion exchange chromatagraphy.