广州市2005年-2009年从业人员乙肝病毒感染状况分析

Analysis on the status of HBV infection of practitioners in Guangzhou city during 2005-2009

目的:了解广州市2005年-2009年从业人员乙型肝炎病毒(HBV)的感染状况,为制定防控措施提供科学依据。方法:用ELISA法检测乙肝病毒表面抗原(HBsAg)、乙肝病毒e抗原(HBeAg)。结果:2005年-2009年从业人员的HBsAg平均阳性率为5.01%(52748/1052570),HBeAg平均阳性率为1.50%(15758/1052570),HBeAg阳性人数占HB-sAg阳性人数的平均百分比为29.87%(15758/52748);HBsAg、HBeAg的阳性率呈逐年下降趋势;年龄组中30～岁组检出HBsAg阳性率最高(5.40%),检出HBeAg阳性率最高的是<30岁组(1.86%),不同年龄组间的HBsAg、HBeAg阳性检出率的差异有统计学意义(P<0.001),HBeAg阳性率随着年龄的增长而下降;男性的HBsAg、HBeAg阳性率比女性高,差异有统计学意义(P<0.001)。结论:广州市从业人员HBV感染状况呈逐年下降趋势。通过全民健康教育、健康促进,接种疫苗等措施可减少HBV感染。

Objective：To understand the status of HBV infection of practitioners in Guangzhou City during 2005-2009,and provide scientific basis for controlling HBV prevalence.Methods： ELISA was used for determination of HBsAg and HBeAg.Results： From 2005 to 2009,the average positive rate of HBsAg was 5.01%（52748/1052570）;the average positive rate of HBeAg was 1.50%（15758/1052570） on the total people tested,the HBeAg positive rates account for 29.87%（15758/52748） of the HBsAg positive people;In view of the age distribution,the HBsAg positive rate of 30-year old group was the highest（5.40%）,and the highest HBeAg positive rate was in 30 years old group（1.86%）,the difference in the age distribution has statistical significance（P〈0.001）.The positive rate of HBeAg decreases with age and the positive rate of HBeAg and HBsAg is higher in males than that in females,with the difference having statistical significances（P〈0.001）.Conclusion： The status of HBV infection in practitioners was decreasing year by year in Guangzhou.Through popularization of prevention health education and health promotion,and inoculation of hepatitis B vaccine,the infection of HBV can be gradually reduced.