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精子DNA损伤对体外受精-胚胎移植后受精及妊娠的影响 被引量:11

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摘要 目的探讨精子DNA;;损伤水平对体外受精-胚胎移植治疗的受精与妊娠的影响。方法检测67例接受体外受精治疗的不育症男性的精子DNA;;损伤水平,分析DNA;;损伤水平与体外受精的受精率、优质胚胎率及妊娠之间的关系。结果精子DNA;;损伤水平与受精率呈负相关(r=-0.34,P<0.05),与优质胚胎率无显著相关性(r=-0.16,P>0.05);治疗后获得妊娠的夫妇的精子SCD阳性率显著低于未获得妊娠的夫妇(7.7%vs 14.3%,P<0.05)。结论精子DNA;;损伤可能与IVF-ET之后受精率、妊娠率的减低相关。
出处 《中国优生与遗传杂志》 2011年第7期111-112,共2页 Chinese Journal of Birth Health & Heredity
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