期刊文献+

婴幼儿腹泻时检测PCT的临床意义 被引量:1

原文传递
导出
摘要 目的探讨检测血清降钙素原(PCT)在婴幼儿腹泻时的临床意义,为婴幼儿腹泻的病因诊断、治疗提供理论依据。方法对我院146例婴幼儿腹泻分为细菌感染组33例和轮状病毒感染组46例和非感染组67例(包括生理性腹泻,如母乳的营养成分超过小儿的生理需要量和消化功能的限度时;喂食不当可引起腹泻,如喂养不定时、量过多或过少或食物成分不适宜等)三组,检测血清PCT进行回顾性分析分析。结果当PCT≥0.1ng/ml时,细菌感染组与轮状病毒感染组相比有显著的统计学意义(χ2=40.1,P<0.05),细菌感染组与非感染组相比有显著的统计学意义(χ2=47.5,P<0.05)。结论细菌感染时血清PCT早期即升高,可作为婴幼儿腹泻病因诊断及治疗有价值的早期指标。
出处 《中国优生与遗传杂志》 2011年第7期125-125,121,共2页 Chinese Journal of Birth Health & Heredity
  • 相关文献

参考文献6

二级参考文献26

  • 1Snider RH Jr, Nylen ES, Becket KL. Procalcitonin and its component peptides in systemic inflammation: immunochemical characterization[J]. J Investig Med, 1997,45(9) :552-560.
  • 2Muller B, White JC, Nylen ES, et al. Ubiquitous expression of the caleitonink-1 gene in multiple tissues in response to sepsis[J]. J Clin Endocrinol Metab, 2001,86( 1 ) :396-404.
  • 3Oberhoffer M, Stonans I, Russwt, rm S, et al. Procalcitonin expression in human peripheral blood mononuclear cells and its modulation by lipopolysaccharides and sepsis-related cytokines in vitra[J]. J Lab Clin Med, 1999.134(1 ) :49-55.
  • 4Whang KT, Vath SD,Becker KL, et al.Procalcitoin and proinflammatory cytokine interactions in sepsis[ J].Shock, 2000,14(1 ) :73-78.
  • 5Nylen ES, Whang KT, Snider RH Jr, et al. Mortality is increased byprocalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis[ J]. Crit Care Med, 1998,26 (6) : 1001-1006.
  • 6Martinez JM, Becket KL, Mailer B, et al. Improved physiologic and metabolic parameters and increased survival with late procaleiton in immunoneutralization in septic pigs. In : 41 st Interscience Conference on Antimicrehiol Agents and Chemotherapy (ICAAC). Chicago, IL,2001.
  • 7Brunkhorst FM, Heins U, Forycki ZF. Kinetics of pmcalcitonin in iatrogenic sepsis[ J]. Intensive Care Med, 1998,24(8) :888-889.
  • 8Schroder J, Staubach KH, Zabel P, et al. Procalcitonin as a marker of severity in septic shock[J]. Langenbecks Arch Sum. 384( 1 ) :33-38.
  • 9Marchini G, Berggren V, Djilalik-Merzoug R, et al. The birth process initiates an acute phase reaction in the fetus-newbom infant[J]. Aeta Paediatr, 2000, 89(9):1082-1086.
  • 10Maire F, Heraud MC, Lorlette Y, et al. The value of procaleitonin in neonatal infecfion[J]. Arch Pediatr, 1999,6(5) :503-509.

共引文献2314

同被引文献6

  • 1Becker KL, Snider R, Nylen ES. Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations [J]. Crit Care Med, 2008, 36(3) : 941 -952.
  • 2Christ- Crain M, Muller B. Biomarkers in respiratory tract infec- tions:diagnostic guides to antibiotic prescription, prognostic markers and mediators[J]. Eur Respir J, 2007, 30(3): 556-573.
  • 3Becker KL, Nylen ES, White JC, et al. Procalcitonin and the cal- citonin gene family of peptides in inflammation, infection, and sep- sis:a journey from calcitonin back to its precursors[ J]. J Clin En- docrinol Metab, 2004, 89(4) : 1512 -1525.
  • 4Linscheid P, Seboeck D, Nylen ES, et al. In vitro and in vivo cal- citoninI gene expression in parenchymal cells: a novel product of humanadipose tissue [ J ]. Endocrinology, 2003, 144 ( 12 ) : 5578 - 5584.
  • 5苏翔宇,程璐,邓雨霞,陈燕平,李苏宜,刘琳.血清PCT水平预测成人恶性肿瘤粒细胞缺乏性发热伴感染的荟萃分析[J].山东医药,2013,53(21):78-80. 被引量:5
  • 6徐卫芹.支气管哮喘患儿治疗前后血清hs-CRP、PCT和BNP检测的临床意义[J].放射免疫学杂志,2013,26(4):495-496. 被引量:4

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部