海南省2005～2010年围产儿死亡率及相关因素分析

Analysis on perinatal mortality and related factors in Hainan from 2005 to 2010

目的:分析海南省围产儿出生缺陷的基本情况及动态变化,探索影响围产儿出生缺陷的原因及预防策略。方法:对2005～2010年海南省某妇幼保健院出生缺陷围产儿的资料进行统计分析。结果:11 483例围产儿中发生出生缺陷286例,出生缺陷发生率为24.91‰;出生缺陷儿死亡率为3.57‰。出生缺陷前5位疾病是:唇腭裂、多指畸形、外耳畸形、先天性心脏病、神经管发育畸形;出生缺陷发生率与孕产妇年龄呈正相关,年龄35岁以上是发生出生缺陷的高危因素;分娩出生缺陷新生儿的孕妇以城乡低收入、低文化人群为主。结论:加强育龄孕妇产前筛查和优生优育教育,营造优生优育的社会和文化环境,降低婴儿出生缺陷的发生率。

Objective：To analyze the basic conditions and dynamic changes of perinatal birth defects in Hainan,explore the causes and prevention strategies of perinatal birth defects. Methods：The perinatal data of birth defects in a maternal and child health hospital of Hainan from 2005 to 2010 were analyzed statistically. Results：Among 11 483 perinatal infants,286 infants were found with birth defects,the incidence was 24.91 ‰;the perinatal mortality was 3.57 ‰.The top five birth defects were cleft lip and palate,polydactylia,ear deformities,congenital heart disease and neural tube defects;there was a positive correlation between the incidence of birth defects and maternal age,35 years old was a high risk factor of birth defects;most of the pregnant women who gave birth to neonates with birth defects belonged to the population with low income and low educational level. Conclusion：Enhancing prenatal screening and education and creating a good social and cultural environment of fertility may reduce the incidence of infantile birth defects.