北京市亚北地区0～6岁儿童维生素D营养状况调查分析

Investigation and analysis on nutritional status of vitamin D in children aged 0～6 years old in northern Asia area in Beijing

目的:了解北京市亚北地区0～6岁儿童维生素D营养状况,为佝偻病防治提供依据。方法:对北京市亚北地区0～6岁210例有可疑VitD摄入不足病史和佝偻病的任何一个非特异性神经精神症状的儿童进行佝偻病相关因素问卷调查、体格检查,采用电化学发光分析仪(竞争法)检测血清25-(OH)D3水平,对结果进行统计学分析。结果:北京市亚北地区0～6岁儿童血清25-(OH)D3平均水平(25.463±7.772)ng/ml,不同年龄段血清25-(OH)D3值差异有统计学意义(P<0.01),性别之间无统计学意义(P>0.05)。维生素D缺乏率24.8%,新生儿、早期婴儿及学龄前儿童维生素D缺乏率高。结论:北京市亚北地区0～6岁儿童维生素D营养状况不如南方地区,应重点加强孕母、早期婴儿及学龄前儿童的维生素D补充。

Objective：To understand the nutritional status of vitamin D in children aged 0~6 years old in northern Asia area in Beijing,provide a basis for the prevention and treatment of rickets. Methods：210 children aged 0~6 years old with suspected medical history of vitamin D deficiency and any non-specific neuropsychiatric symptoms in northern Asia area in Beijing were surveyed by a questionnaire about rickets related factors,and all of the children received physical examination,electrochemical luminescence analyzer（competition method） was used to detect the serum level of 25-（OH）D3,then the results were analyzed statistically. Results：The average serum level of 25-（OH）D3 in the children aged 0~6 years old in northern Asia area in Beijing was（25.463±7.772） ng·ml-1.There was significant difference in serum level of 25-（OH）D3 among different age groups（P0.01）,but there was no significant difference between boys and girls（P0.05）.The incidence of vitamin D deficiency was 24.8%.The incidences of vitamin D deficiency in neonates,early infants and preschool children were high. Conclusion：The nutritional status of vitamin D in children aged 0~6 years old in northern Asia area in Beijing is inferior to that in South Asia area,the supplement of vitamin D in pregnant women,early infants and preschool children should be strengthened.