儿童微小病变型肾病综合征中医证型与年龄、性别的关系

Relationship between syndrome pattern of Chinese medicine and age or sex in children with minimal lesion nephrotic syndrome

目的探讨儿童微小病变型肾病综合征的中医证型与年龄、性别的关系。方法在肾穿刺活检前24 h内对133例原发性微小病变型肾病综合征住院患儿进行中医辨证分型,分析中医证型与年龄、性别的关系。结果患儿年龄2.0～16.0(7.01±3.63)岁;男101例,女32例,男女之比为3.2∶1。年龄分期分布以学龄前期最多,共50例占37.6%,其次为学龄期和青春期,分别是38例和35例,分别占28.6%和26.0%,婴幼儿期最少,共10例占7.6%。中医辨证分5型:肺脾气虚型38例占28.6%;脾虚湿困型17例占12.8%;脾肾阳虚型44例占33.1%;肝肾阴虚型13例占9.8%,气阴两虚型21例占15.8%,其中以肺脾气虚型和脾肾阳虚型为主要表现类型。结论微小病变型肾病综合征的中医证型与年龄、性别之间存在相关性,探讨其关系可以促进对本病的认识,有利于及时对此类疾病的诊断、治疗进行中医干预。

Objective It is to approach the relationship between syndrome pattern of Chinese medicine and age or sex in children with minimal lesion nephrotic syndrome.Methods The syndrome pattern of Chinese medicine of 133 hospitalization children with minimal lesion nephrotic syndrome were carried out within 24 h before renal needle biopsy.The relationship between syndrome pattern of Chinese medicine and age or sex was analyzed.Results The age of the 133 children was 2.0-16.0（7.01±3.63） years old.There were 101 boys and 32 girls,and the ratio of male and female was 3.2：1.According to age stage,preschool age was the most,up to a total of 50 cases,accounting for 37.6%;followed by school-age and adolescence,respectively 38 cases and 35 cases,respectively 28.6% and 26.0%;infants and young children were the least,accounting for 7.6% of 10 cases.According to syndrome pattern of Chinese medicine,38 cases were asthenia of pulmonosplenic Qi,accounting for 28.6%;17 cases were splenasthenic fluid-retention,accounting for 12.8%;44 cases were asdthenic splenonephro-Yang,accounting for 33.1%;13 cases were hepatic and renal Yin deficiency,accounting for 9.8%;21 cases were deficiency of both Qi and Yin,accounting for 15.8%.The asthenia of pulmonosplenic Qi type and the asdthenic splenonephro-Yang were the mainly types.Conclusion The syndrome pattern of Chinese medicine of minimal lesion nephrotic syndrome has correlation with age and sex.Approaching the relations could promote the cognition on this disease and could make for the intervention of traditional Chinese medicine for the diagnosis and treatment of the disease in time.