摘要
目的了解我院抗菌药物的应用情况及细菌分离和耐药率的特点。方法调取我院2009年抗菌药物的出库数据,采用限定日剂量法分析抗菌药物的应用情况,同时采用API半自动微生物鉴定系统及药敏卡进行病原菌鉴定及药敏实验。结果我院临床抗菌药物的使用以大环内酯类和氟喹诺酮类为主,其次是第二代头孢菌素和内酰胺酶抑制剂复方制剂;同期临床分离的细菌以革兰阴性杆菌为主。结论我院临床分离的革兰阴性杆菌对常用抗菌药物的耐药现象严重,应限制广谱抗菌药物的应用。
Objective To investigate the utilization of antibiotics,isolation of bacteria and the characteristics bacterial resistance rate in our hospital in 2009.Methods The data about consumption of the antibiotics was collected from pharmacy department,and the utilization of antibiotics was analyzed using DDD analysis.The API half-automatic microbiological system and Vitek2 GNS seriation cards were used to identify the clinical isolated pathogenic bacteria and conduct drug susceptibility tests.Results The consumption of macrolides and quinolones were predominant.And second generation of cephalosprins and other β-lactam antibiotics were secondary.Gram-negative bacilli were predominant among the clinical isolated pathogenic bacteria.Conclusion Clinical isolated gram-negative bacilli shows severe drug resistance to general antibiotics in our hospital.The utilization of broad spectrum antibiotics should be restricted to deceasing resistant.
出处
《中国药事》
CAS
2011年第7期731-733,共3页
Chinese Pharmaceutical Affairs
关键词
抗菌药物
应用
细菌耐药性
分析
antibiotics
utilization
bacterial resistance
analysis
