与药物相关的眼部毒性损害研究进展

Ocular toxicity assodated with drugs

与药物相关的眼部毒性损害多种多样。由于药物的种类、剂量、暴露方式等不同，其眼部毒性表现及损害程度亦有很大差别，临床诊断困难。如果不能及时诊断和立即阻止其对眼部的继续损害并对症治疗，往往会导致患者视力下降，甚至永久性视力丧失。因此，有必要就相关药物引起眼部毒性损害的临床特点、发病机制、诊断、治疗及预防等方面进行综述，旨在引起临床眼科医师的广泛关注。

The clinical manifestation of ocular toxicity associated with drugs are various. The ocular toxic manifestations and the degree of impairment are different due to the variety, dose, and routes of exposure and so on. It is difficult to diagnose the cause of the toxicity . If we can＇t find the toxic factor immediately, stop the damage to the eyes, and treat in time, the patient＇s vision will be impaired or even lose. This article reviews ocular toxicity caused by drugs, including the variety of drugs, clinical manifestations, etiopathogenisis, diagnosis, treatment and prevention.